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Gene Expression Literature Summary
Assay
Age
Immunohistochemistry (whole mount)
11 DPC

3 matching records from 3 references.

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Flt4  FMS-like tyrosine kinase 4   (Synonyms: Flt-4, VEGFR3, VEGFR-3)
Results  Reference
1J:213676 Dartsch N, Schulte D, Hagerling R, Kiefer F, Vestweber D, Fusing VE-cadherin to alpha-catenin impairs fetal liver hematopoiesis and lymph but not blood vessel formation. Mol Cell Biol. 2014 May;34(9):1634-48
1*J:244466 Karpanen T, Padberg Y, van de Pavert SA, Dierkes C, Morooka N, Peterson-Maduro J, van de Hoek G, Adrian M, Mochizuki N, Sekiguchi K, Kiefer F, Schulte D, Schulte-Merker S, An Evolutionarily Conserved Role for Polydom/Svep1 During Lymphatic Vessel Formation. Circ Res. 2017 Apr 14;120(8):1263-1275
1J:177405 Zhang L, Zhou F, Han W, Shen B, Luo J, Shibuya M, He Y, VEGFR-3 ligand-binding and kinase activity are required for lymphangiogenesis but not for angiogenesis. Cell Res. 2010 Dec;20(12):1319-31

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory